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NeurOne高精度腦電測(cè)量系統(tǒng)

產(chǎn)品詳細(xì)介紹NeurOne高精度腦電測(cè)量系統(tǒng)一、產(chǎn)品概述：NeurOneEEG/ERP高精度腦電測(cè)量系統(tǒng)是芬蘭Mega公司開(kāi)發(fā)的創(chuàng)新型腦科學(xué)研究，NeurOne認(rèn)知神經(jīng)科學(xué)測(cè)量系統(tǒng)利用世界最新的數(shù)字信號(hào)處理技術(shù)發(fā)展，目前是全世界性能最好的神經(jīng)科學(xué)測(cè)量系統(tǒng)并提供了更加精確與干凈的信號(hào)質(zhì)量、更高的采樣率、模塊化解決方案，和在數(shù)字信號(hào)加工過(guò)程中利用最新處理手段,使其更加具有靈活性和擴(kuò)展性。NeurOne是一個(gè)多功能系統(tǒng)，廣泛應(yīng)用于不同的認(rèn)知神經(jīng)科學(xué)、心理與行為科學(xué)以及人因工程與工效學(xué)等研究領(lǐng)域。二、多模態(tài)腦功能研究：NeurOne系統(tǒng)可以與fMRI功能性核磁共振、fNIRS功能性近紅外光譜腦成像或者TMS經(jīng)顱磁刺激器結(jié)合進(jìn)行多模態(tài)腦功能實(shí)驗(yàn)研究；NeurOne提供了專為與TMS經(jīng)顱磁刺激器一起使用的功能模塊，有特殊還原技術(shù)在短延時(shí)情況下來(lái)消除磁制品影響。先進(jìn)的頭盒設(shè)計(jì)使AC交流電和DC直流電信號(hào)可單獨(dú)或同時(shí),新的創(chuàng)新Tesla核磁腦電放大器給NeurOne帶來(lái)MRI兼容性。三、技術(shù)功能特點(diǎn)：NeurOne挑戰(zhàn)傳統(tǒng)的認(rèn)知神經(jīng)實(shí)驗(yàn)室ERP系統(tǒng):24Bit高分辨率每通道最高可達(dá)80,000Hz超高速采樣率高精度放大器技術(shù)可升級(jí)為NeurOneBrainstorm系統(tǒng),最高達(dá)1200導(dǎo)聯(lián)NeurOne設(shè)備具有很明顯的技術(shù)領(lǐng)先優(yōu)勢(shì)，決不以犧牲數(shù)據(jù)質(zhì)量來(lái)追求通道的數(shù)量、縮短準(zhǔn)備時(shí)間或者降低成本。其中，NeurOne放大器每個(gè)80導(dǎo)，包括8個(gè)雙極導(dǎo)聯(lián)，還有8導(dǎo)High-level外接信號(hào)輸入。由于它的頻帶足夠?qū)挘―C～3500Hz）、采樣率足夠高（256-1200導(dǎo)，每導(dǎo)可達(dá)20000Hz，單導(dǎo)記錄最高可達(dá)80000Hz），還可用雙極或單極同時(shí)記錄許多其他的生理信號(hào)（如ECG心電、EMG肌電、EEG腦電等），一方面可以去除心電和肌電的干擾，另一方面可以進(jìn)行腦活動(dòng)過(guò)程與其他生理系統(tǒng)的綜合研究。同時(shí)NeurOne的放大器參數(shù)足夠高，性能足夠穩(wěn)定，可以進(jìn)行聽(tīng)覺(jué)腦干誘發(fā)電位的記錄和研究。輸入阻抗為1 Gohm，共模抑制比 106 dB。 NeurOne是建立在高保真記錄的基礎(chǔ)上，能夠提供完全原始的高保真數(shù)據(jù)，不需要屏蔽和濾波，信號(hào)不失真。四、腦電超掃描技術(shù)NeurOne腦電超掃描系統(tǒng)每個(gè)放大器的Headbox由64個(gè)單極、8個(gè)雙極和8個(gè)high level輸入接口組成，共計(jì)80導(dǎo)，每導(dǎo)的采樣率能達(dá)到20000Hz，最高可以達(dá)到80000Hz。團(tuán)體超掃描腦電測(cè)試平臺(tái)每套系統(tǒng)可提供多至2-30個(gè)放大器（共計(jì)128/1200導(dǎo)）的協(xié)調(diào)同步,并可選擇支持視頻同步。NeurOne系統(tǒng)最高支持1200高導(dǎo)聯(lián)，并可確保所有通道的同步采集。精心設(shè)計(jì)的啟動(dòng)和時(shí)間鎖定功能確保系統(tǒng)中所有通道無(wú)相位偏差。所有的通道都使用高質(zhì)量的24位A/D模擬數(shù)字芯片來(lái)處理數(shù)據(jù)。五、多功能應(yīng)用：　1、Hyperscanning腦電超掃描研究:NeurOne腦電超掃描系統(tǒng)的模塊化設(shè)計(jì)可以提供多達(dá)4人實(shí)時(shí)同步進(jìn)行腦功能超掃描測(cè)試使用系統(tǒng)，并支持完全同步視頻的攝影機(jī)。使用創(chuàng)新的Brainstorm超掃描技術(shù) (Multi Syncbox)，支持多達(dá)10個(gè) NeurOne主機(jī)系統(tǒng)實(shí)時(shí)同步，允許最多30人使用30個(gè)放大器同時(shí)工作–均由一臺(tái)電腦記錄。2、EEG-fNIRS多模態(tài)研究: NeurOne多模態(tài)腦功能測(cè)試系統(tǒng)可以和fNIRS（高密度近紅外腦功能成像系統(tǒng)）搭配使用，將EEG和fNIRS進(jìn)行整合發(fā)揮二者的優(yōu)勢(shì)，EEG的時(shí)間分辨率高，但是空間分辨率低；fNIRS的時(shí)間分辨率低，實(shí)時(shí)性較差，但是空間分辨率高。為了準(zhǔn)確、全面、實(shí)時(shí)的測(cè)量大腦在認(rèn)知過(guò)程中的活動(dòng)，實(shí)現(xiàn)全面、實(shí)時(shí)的腦成像方式無(wú)疑是一種更好的策略。結(jié)合EEG與fNIRS的多模態(tài)腦成像技術(shù)在認(rèn)知神經(jīng)科學(xué)研究中有著很好的應(yīng)用前景，同時(shí)還可搭建多模態(tài)腦-機(jī)接口系統(tǒng)。3、EEG-fNIRS多模態(tài)腦機(jī)接口研究:傳統(tǒng)基于單一模態(tài)腦電(EEG)腦-機(jī)接口易受環(huán)境噪聲干擾、分類精度低等問(wèn)題,在EEG腦-機(jī)接口的研究基礎(chǔ)上,引入功能近紅外光譜成像(function NearInfrared Spectroscopy,fNIRS)技術(shù),可以自行設(shè)計(jì)EEG-fNIRS多模態(tài)腦-機(jī)接口的實(shí)驗(yàn)范式,研究最重要的特征提取與分類環(huán)節(jié)，同時(shí)SIMULINK驅(qū)動(dòng)程序可在訂單中選購(gòu)，并提供BCI腦機(jī)接口應(yīng)用程序: BCI2000可免費(fèi)提供給NeurOne用戶。4、EEG-TMS多模態(tài)研究: NeurOne多模態(tài)腦功能測(cè)試系統(tǒng)可以和TMS（經(jīng)顱磁刺激器）搭配使用。高動(dòng)態(tài)輸入范圍（+/-430mV的直流電模式以及+/-86mV的交流電模式），較大的模擬帶寬（直流輸出3500HZ），讓TMS保持較低的偽影，使得分析大腦活動(dòng)的潛伏期更短。此外，TMS擁有硬件弱音功能以及在線偽影消除的軟件功能。此外我們?cè)黾恿薊EG采樣同步觸發(fā)新功能。觸發(fā)器由刺激系統(tǒng)軟件發(fā)出（ErgoLAB刺激編譯軟件、Presentation軟件, Superlab軟件, E-Prime軟件），這些觸發(fā)信號(hào)能夠通過(guò)NeurOne主控器傳到TMS設(shè)備上。NeurOne可以在持續(xù)的EEG采樣信號(hào)中發(fā)出觸發(fā)脈沖，產(chǎn)生更精確的TMS，減少偽影，更容易進(jìn)行偽影去除。NeurOne結(jié)合TMS案例應(yīng)用：http://www.kingfar.cn/newsShow_88.html5、EEG-fMRI多模態(tài)研究: NeurOne Tesla多模態(tài)腦功能測(cè)試系統(tǒng)使得同時(shí)測(cè)量MRI和EEG成為可能。利用NeurOne SyncboxEEG所獲得的數(shù)據(jù)和MRI掃描是同步的(例如4或10MHz)。高動(dòng)態(tài)輸入范圍(+/- 430 mV的直流電模式和 +/-86 mV的交流電模式)結(jié)合模擬帶寬(直流輸出3500 Hz) ,使利用高梯度力度獲得精確信號(hào)毫無(wú)風(fēng)險(xiǎn)。應(yīng)用領(lǐng)域：EEG/EP測(cè)量ERP研究EEG +TMS結(jié)合多模態(tài)腦功能研究EEG +fMRI結(jié)合多模態(tài)腦功能研究多通道EMG肌電圖研究群組超掃描研究（多達(dá)4人4視頻攝像機(jī)完全同步）其他神經(jīng)科學(xué)的測(cè)量其他心理測(cè)量 NeurOne放大器參數(shù)：?每個(gè)Headbox 有64導(dǎo)單極導(dǎo)聯(lián)；?每個(gè)Headbox 有16導(dǎo)雙極導(dǎo)聯(lián)；?每個(gè)Headbox 有16導(dǎo)High Level 導(dǎo)聯(lián)；?采樣率：512導(dǎo)同時(shí)采集，每導(dǎo)可達(dá)20,000 Hz ；?所有導(dǎo)聯(lián)均同步采集信號(hào)，最大支持1200高導(dǎo)聯(lián)，?支持超掃描技術(shù)Hyperscanning最多支持30人同步采集團(tuán)體腦電數(shù)據(jù)；?支持多模態(tài)技術(shù)，含EEG-TMS，EEG-fNIRS，EEG-fMRI等研究技術(shù)方案?A/DResolution：24 Bit ；?輸入阻抗：1 GOhms ；?共模抑制比（CMRR）：106 dB ；?帶寬（Bandwidth）：DC ～ 3500 Hz ；?低通濾波：DC（10000 Hz）；-3 dB（7000 Hz）；?高通濾波： -3 dB（0.16 Hz）；?輸入噪聲（InputNoise.）（DC Mode）：<0.8uV RMS (0-200 Hz)，<2.0uV RMS(DC-3500 Hz) ；?輸入范圍（FullScale Input Range）（DC Mode）：+/- 430 mV ；?系統(tǒng)增益（SystemGain）（DC Mode）：10 ；?靈敏度（Sensitivity）（DC Mode)：51 nV/bit ；?輸入噪聲（InputNoise.）（AC Mode）：<0.6uV RMS (0.16-200 Hz)，<1.5uV RMS (0.16-3500 Hz) ；?輸入范圍（FullScale Input Range）（AC Mode）：+/- 4.3 mV ；?系統(tǒng)增益（SystemGain）（AC Mode）：50 ；?靈敏度（Sensitivity）（AC Mode）：0.51 nV/bit ；?數(shù)字化（TTL）輸入：8 Bit非隔離輸入觸發(fā)，2個(gè)隔離輸入/輸出?High Level 輸入范圍：+/- 5 V ；或+/- 10 V?阻抗：1K Ohm ～ 50 K Ohm ；?Headbox 體積（h x w x d）：20 x 7 x 16cm, 每 64 導(dǎo)；?Headbox 重量：0.68 kg。?Main unit體積（H x W x D）：33×12×27 cm,160導(dǎo)系統(tǒng)主機(jī)?Main unit重量：3.6?安全規(guī)范：EN60601-1，EN 60601-1-1，EN 60601-1-2EN60601-1-4，EN60601-2-26NeurOne用戶請(qǐng)注意：注意 – 僅用于科研，不用于診斷過(guò)程,設(shè)備可用于非臨床實(shí)驗(yàn)研究。PUBLICATIONS USING NEURONE EEG/ERP ORNEURONE TESLA :1. A platform for realtime processing of biosignalsfor monitoring purposes. PITK?NEN,PAAVO. Master of Science Thesis. Tampere University of Technology. May 2012. InFinnish2. A New Platform for Realtime BCI Applications. Paavo Pitk?nen1,2,Jukka Kinnunen2, Tarmo Lipping1 (IEEE,Senior Member). 1 Tampere University Of Technology, 2 Mega Electronics Ltd. Poster at Berlin BCI meeting 20123. Visual ERP P3 amplitude and latency in standaloneand embedded visual processing task. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:781-4.doi: 10.1109/IEMBS.2011.6090179. Korpela J, Huotilainen M. Brain Work ResearchCentre, Finnish Institute of Occupational Health, Helsinki, Finland. [email protected]. The effect of automatic blink correction onauditory evoked potentials. Korpela,J. ; Brain Work Res. Centre, Finnish Inst. of Occupational Health, Helsinki,Finland ; Vigario, R. ; Huotilainen, M. 10.1109/EMBC.2012.63460095. Breakfast high in whey protein or carbohydratesimproves coping with workload in healthy subjects. Nora Sihvola a1, Riitta Korpela a1, Andreas Henelius a2, Anu Holm a2 a3,Minna Huotilainen a2, Kiti Müller a2,Tuija Poussa a4, Kati Pettersson a2,Anu Turpeinen a5 and Katri Peuhkuri a1 c1.a1 Institute of Biomedicine, Medical NutritionPhysiology, Pharmacology, University of Helsinki, PO Box 63, HelsinkiFIN-00014, Finland. a2 Finnish Institute of Occupational Health,Brain and Technology Team, Topeliuksenkatu 41 aA, Helsinki FIN-00250, Finland. a3 Department of Clinical Neurophysiology, Hospital District of Satakunta,Sairaalantie 3, Pori FIN-28500, Finland a4 Stat-Consulting,Vahverokatu 6, Nokia FIN-37130, Finland a5 ValioLimited, PO Box 30, VALIO, Helsinki FIN-00039, Finland British Journal ofNutrition, 20136. Pilot Study ofAcupuncture Point Laterality: Evidence from Heart Rate Variability. Guangjun Wang, Yuying Tian, ShuyongJia,Wenting Zhou, and Weibo Zhang.Institute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences, 16Dongzhimennei, Nanxiaojie, Dongchen District, Beijing 100700, China Evidence-BasedComplementary and Alternative Medicine. Volume 2013 (2013), Article ID 476064,7 pages http://www.hindawi.com/journals/ecam/aip/476064/7. Algorithm forautomatic analysis of electro-oculographic data.Kati Pettersson1*, Sharman Jagadeesan1, Kristian Lukander1,Andreas Henelius1, Edward H?ggstr?m2 andKiti Müller11Brain Work Research Center, FinnishInstitute of Occupational Health, Topeliuksenkatu 41aA, Helsinki 00250,Finland.2Electronics Research Laboratory, Departmentof Physics, University of Helsinki, P. O. Box 64, Gustaf H?llstr?min katu 2,Helsinki FIN-00014, Finland.BioMedicalEngineering OnLine 2013 12:110.8. Brain-statedependent brain stimulation: Real-time EEG alpha band analysis using slidingwindow FFT phase progression extrapolation to trigger an alpha phase locked TMSpulse with 1 millisecond accuracy.Christoph Zrenner,Johannes Tünnerhoff , Carl Zipser, Florian Müller-Dahlhaus , Ulf ZiemannCenter forNeurology, Tübingen University, Hoppe-Seyler-Str. 3, 72076 Tübingen, GermanyBrainStimulation: Basic, Translational, and Clinical Research in Neuromodulation:Volume 8, Issue 2, A1-A10, 169-4389. Behavioral andelectrophysiological evidence for fast emergence of visual consciousness.Henry Railo1,2,3,*,Antti Revonsuo1,2,3,4 and Mika Koivisto1,2,31Department of Psychology, University ofTurku, 20014, Finland; 2Centre for Cognitive Neuroscience, University of Turku, 20014, Finland;3Brain and Mind Centre, University of Turku,20014, Finland; 4School of Bioscience, University of Sk?vde,SE-54128, SwedenNeuroscience ofConsciousness, 2015, 1–1210. Fastdetermination of MMN and P3a responses to linguistically and emotionallyrelevant changes in pseudoword stimuliSatu Pakarinen,Laura Sokka, Marianne Leinikka, Andreas Henelius, Jussi Korpela,MinnaHuotilainenFinnish Institute ofOccupational Health, Helsinki, FinlandNeuroscienceLetters 577 (2014) 28–3311. Alterationsin attention capture to auditory emotional stimuli in job burnout: Anevent-related potential studyLaura Sokka a, Minna Huotilainen a, Marianne Leinikka a, Jussi Korpela a, Andreas Henelius a,Claude Alain b,c, Kiti Müller a,Satu Pakarinenaa Finnish Institute of Occupational Health,Topeliuksenkatu 41 a A, 00250 Helsinki, Finlandb Rotman Research Institute, Baycrest Centrefor Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1c Department of Psychology, University ofToronto, Toronto, Ontario, CanadaInternationalJournal of Psychophysiology 94 (2014) 427–43612. Brain-statedependent non-invasive brain stimulation using closed-loop real-time EEG signalanalysis to trigger a TMS pulse with millisecond accuracyC. Zrenner, J.Tünnerhoff, C. Zipser, F. Müller-Dahlhaus, U. ZiemannUniversity ofTübingen, Center of Neurology, Tübingen, GermanySocietyProceedings / Clinical Neurophysiology 126 (2015) e63–e17013. BilateralHegu Acupoints Have the Same Effect on the Heart Rate Variability of theHealthy SubjectsWang Guangjun, TianYuying, Jia Shuyong, ZhouWenting, and ZhangWeiboInstitute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences,Beijing 100700,ChinaHindawi PublishingCorporationEvidence-BasedComplementary and Alternative MedicineVolume 2014, ArticleID 106940, 5 pages (http://dx.doi.org/10.1155/2014/106940)14. AcupunctureRegulates the Heart Rate VariabilityGuangjun Wang,Yuying Tian, Shuyong Jia, Wenting Zhou, Weibo ZhangInstitute ofAcupuncture and Moxibustion, China Academy of Chinese Medical Sciences,Beijing, ChinaJ AcupunctMeridian Stud 2015;8(2):94-9815. Closed-LoopNeuroscience and Non-Invasive Brain Stimulation: A Tale of Two LoopsChristoph Zrenner,Paolo Belardinelli, Florian Müller-Dahlhaus and Ulf ZiemannBrain Network andPlasticity Laboratory, Department of Neurology and Stroke and Hertie-Institutefor Clinical Brain Research, University of Tübingen, Tübingen, GermanyFrontiers inCellular Neuroscience, April 2016, Volume 10, Article 9216. Physiologicalprocesses non-linearly affect electrophysiological recordings duringtranscranial electric stimulationNoury, N., et al.,NeuroImage (2016), http://dx.doi.org/10.1016/j.neuroimage.2016.03.06517. Job burnout is associated with dysfunctions inbrain mechanisms ofvoluntary and involuntary attention Laura Sokka, Marianne Leinikka, JussiKorpela, Andreas Henelius, Lauri Ahonen,Claude Alain, Kimmo Alho, MinnaHuotilainen, http://dx.doi.org/10.1016/j.biopsycho.2016.02.01018. Shifting ofattentional set is inadequate in severe burnout: Evidence from an event-relatedpotential studyLaura Sokka, MarianneLeinikka, Jussi Korpela, Andreas Henelius, Jani Lukander, Satu Pakarinen, KimmoAlho, Minna Huotilainen. PII: S0167-8760(16)30853-4 DOI: doi:10.1016/j.ijpsycho.2016.12.004

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