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馬力耕，男，1965年出生。教授，博士生導(dǎo)師。1987畢業(yè)于河北師范大學(xué)生物學(xué)系，獲學(xué)士學(xué)位；1990畢業(yè)于河北師范大學(xué)生物學(xué)系植物生理學(xué)專(zhuān)業(yè)，獲碩士學(xué)位；1997 畢業(yè)于中國(guó)農(nóng)業(yè)大學(xué)生物學(xué)院生物化學(xué)專(zhuān)業(yè)，獲博士學(xué)位。 論文情況 論文標(biāo)題為：《MicroRNAs and their targets from Arabidopsis to rice: half conserved and half diverged》，None 論文標(biāo)題為：《The SNW Domain of SKIP Is Required for Its Integration into the Spliceosome and Its Interaction with the Paf1 Complex in Arabidopsis.》，Abstract SKIP is a conserved protein from yeasts to plants and humans. In plant cells, SKIP is a bifunctional regulator that works in the nucleus as a splicing factor by integrating into the spliceos... 論文標(biāo)題為：《SKIP Confers Osmotic Tolerance during Salt Stress by Controlling Alternative Gene Splicing in Arabidopsis.》，Abstract Deciphering the mechanisms underlying plant responses to abiotic stress is key for improving plant stress resistance. Much is known about the regulation of gene expression in response to sal... 論文標(biāo)題為：《The ATP-Binding Cassette Transporter ABCB19 Regulates Postembryonic Organ Separation in Arabidopsis》，The phytohormone auxin plays a critical role in plant development, including embryogenesis, organogenesis, tropism, apical dominance and in cell growth, division, and expansion. In these processes, th... 論文標(biāo)題為：《USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing》，Post-translational histone modifications play important roles in regulating chromatin structure and function. Histone H2B ubiquitination and deubiquitination have been implicated in transcriptional re... 論文標(biāo)題為：《A Companion Cell–Dominant and Developmentally Regulated H3K4 Demethylase Controls Flowering Time in Arabidopsis via the Repression of FLC Expression》，F(xiàn)lowering time relies on the integration of intrinsic developmental cues and environmental signals. FLC and its downstream target FT are key players in the floral transition in Arabidopsis. Here, we c... 論文標(biāo)題為：《Overexpression of a histone H3K4 demethylase, JMJ15, accelerates flowering time in Arabidopsis》，The methylation of histone 3 lysine 4 (H3K4) is essential for gene activation. Flowering Locus C (FLC), an important flowering repressor, quantitatively regulates flowering time in Arabidopsis and its... 論文標(biāo)題為：《SKIP Is a Component of the Spliceosome Linking Alternative Splicing and the Circadian Clock in Arabidopsis》，Circadian clocks generate endogenous rhythms in most organisms from cyanobacteria to humans and facilitate entrainment to environmental diurnal cycles, thus conferring a fitness advantage. Both transc... 論文標(biāo)題為：《Overexpression of AtBMI1C, a Polycomb Group Protein Gene, Accelerates Flowering in Arabidopsis》，Polycomb group protein (PcG)-mediated gene silencing is emerging as an essential developmental regulatory mechanism in eukaryotic organisms. PcGs inactivate or maintain the silenced state of their tar... 論文標(biāo)題為：《Conservation and divergence of the histone H2B monoubiquitination pathway from yeast to humans and plants》，Histone ubiquitination plays a critical role in the regulation of transcription, and histone H2B monoubiquitination (H2Bub1) is mainly associated with transcriptional activation. Recent studies in yea... 論文標(biāo)題為：《Characterization of the genome expression trends in the heading-stage panicle of six rice lineages》，a b s t r a c t a r t i c l e i n f o To study how changes in gene regulation shape phenotypic variations in rice, we performed a comparative analysis of genome expression in the heading-stage panicle... 論文標(biāo)題為：《Histone H2B Monoubiquitination in the Chromatin of FLOWERING LOCUS C Regulates Flowering Time in Arabidopsis》，Ubiquitination is one of many known histone modifications that regulate gene expression. Here, we examine the Arabidopsis thaliana homologs of the yeast E2 and E3 enzymes responsible for H2B monoubiqu... 項(xiàng)目情況 項(xiàng)目標(biāo)題為：《植物基因組層面的可變剪切研究》，項(xiàng)目類(lèi)型為：國(guó)家級(jí)項(xiàng)目;其他項(xiàng)目;2013年植物基因組學(xué)國(guó)家重點(diǎn)實(shí)驗(yàn)室開(kāi)放課題 項(xiàng)目標(biāo)題為：《細(xì)胞信息》，項(xiàng)目類(lèi)型為：國(guó)家杰出青年科學(xué)基金 項(xiàng)目標(biāo)題為：《細(xì)胞外鈣調(diào)素對(duì)基因表達(dá)調(diào)控研究》，項(xiàng)目類(lèi)型為：面上項(xiàng)目 項(xiàng)目標(biāo)題為：《細(xì)胞外鈣調(diào)素對(duì)花粉萌發(fā)調(diào)控作用的信號(hào)轉(zhuǎn)導(dǎo)機(jī)理研究》，項(xiàng)目類(lèi)型為：青年科學(xué)基金項(xiàng)目 項(xiàng)目標(biāo)題為：《基因可變剪接參與擬南芥生態(tài)型間雜交不親合調(diào)控研究》，項(xiàng)目類(lèi)型為：面上項(xiàng)目 項(xiàng)目標(biāo)題為：《植物響應(yīng)鹽堿脅迫的組蛋白修飾和基因轉(zhuǎn)錄調(diào)控機(jī)制》，項(xiàng)目類(lèi)型為：國(guó)家級(jí)項(xiàng)目;國(guó)家973計(jì)劃 ;民口973

產(chǎn)品詳細(xì)介紹 nG12500系列中試型高壓納米均質(zhì)機(jī)（高壓微射流納米均質(zhì)機(jī)） nG12500系列高壓均質(zhì)機(jī)是用于中試工藝微調(diào)和小規(guī)模生產(chǎn)的終極解決方案，采用STANSTED專(zhuān)利的HYD-LOK構(gòu)造，克服了其它常規(guī)高壓均質(zhì)機(jī)的限制和繁瑣，全范圍工作壓力下都可以高效的均質(zhì)分散您的珍貴樣品，具有精確、始終如一、重現(xiàn)性好和可調(diào)比例壓力控制的特點(diǎn)，最大壓力達(dá)4000Bar(58000psi)，可在位清洗和滅菌，并且非常方便清洗和維護(hù)。使用STANSTED精密耐用的電動(dòng)液壓系統(tǒng)和精確的閥控制系統(tǒng)，nG12500系列高壓均質(zhì)機(jī)可解決各種復(fù)雜的應(yīng)用和小規(guī)模化的生產(chǎn)。具有如下特點(diǎn)：具有單增壓器和雙增壓器版本，可在1,500 psi (10 MPa) 到58,000 psi (400 MPa)壓力下連續(xù)不間斷運(yùn)行，流量最高可達(dá)20升每小時(shí)。滿(mǎn)足實(shí)驗(yàn)室和中試規(guī)模生產(chǎn)的多功能使用。壓力平衡負(fù)載均質(zhì)閥和噴射碰撞相互作用腔可互換。PLC電子控制和監(jiān)控系統(tǒng)，按鍵操作。多級(jí)均質(zhì)模塊可選。增壓器處理單元熱交換器和出料熱交換器。帶計(jì)算機(jī)連接端口用于數(shù)據(jù)采集。溫度控制模塊和不同進(jìn)樣系統(tǒng)選件供選擇。不銹鋼外殼帶透明安全蓋。型號(hào)處理單元工作壓力處理量nG12500nG12500S-4-054000巴5升每小時(shí)nG12500S-2-102100巴10升每小時(shí)nG12500T-4-104000巴10升每小時(shí)nG12500T-2-202100巴20升每小時(shí)Stansted Fluid Power Ltd(SFP)公司，專(zhuān)業(yè)于設(shè)計(jì)和制造實(shí)驗(yàn)、中試和生產(chǎn)型超高壓設(shè)備，系統(tǒng)最大壓力可達(dá)14000bar (200,000psi , 1400MPa)。SFP的HYD-LOK概念是高壓均質(zhì)的特別設(shè)計(jì)與應(yīng)用，它除了具有傳統(tǒng)高壓高剪切的特點(diǎn)和效益，還賦于更優(yōu)越的性能，更穩(wěn)定的可靠性和更有樂(lè)趣的用戶(hù)體驗(yàn)。該HYD-LOK系統(tǒng)的構(gòu)造技術(shù)由SFP發(fā)明并具有專(zhuān)利，主體的壓力產(chǎn)生裝置附在帶有支架的液壓緊固裝置里，這種獨(dú)特的構(gòu)造可實(shí)現(xiàn)自動(dòng)化程度極高的最高端使用特性，以適應(yīng)現(xiàn)今高壓均質(zhì)應(yīng)用上的嚴(yán)格要求：堅(jiān)固耐用、高穩(wěn)定性和制藥衛(wèi)生級(jí)操作，它是高壓均質(zhì)自動(dòng)化成功應(yīng)用的關(guān)鍵。HYD-LOK系統(tǒng)的原理和優(yōu)點(diǎn)：快速無(wú)需工具進(jìn)入增壓器內(nèi)部HYD-LOK增壓裝置作為SFP高壓均質(zhì)機(jī)的主要部件，無(wú)需特殊技能和培訓(xùn)即可輕易維護(hù).僅數(shù)秒鐘即可釋放壓力并打開(kāi)增壓器，即可拆移、檢查、清洗、或者更換增壓器部件。在位清洗和滅菌HYD-LOK的特殊設(shè)計(jì)克服了傳統(tǒng)高壓泵系統(tǒng)的難題，可完全折開(kāi)清洗，并可以在位滅菌。快速更換和檢測(cè)閥組件SFP系列均質(zhì)機(jī)擁有多種選配裝置，以適應(yīng)不同樣品的均質(zhì)要求。SFP有各種不同的均質(zhì)閥，可以在幾秒鐘內(nèi)非常快速的拿取、拆開(kāi)、清洗、檢查、維護(hù)和更換。良好的穩(wěn)定性HYD-LOK技術(shù)將各部件鉗制在同一線(xiàn)上用于抵抗系統(tǒng)運(yùn)行時(shí)各部件產(chǎn)生的軸向運(yùn)動(dòng)，因此相比于傳統(tǒng)的高壓均質(zhì)機(jī)密封的磨損和疲勞可大大減少。雙增壓器平穩(wěn)遞送系統(tǒng)SFP雙增壓型號(hào)系列高壓均質(zhì)機(jī)適用于大容量和更高級(jí)均質(zhì)分散要求。雙增壓器采用電動(dòng)同步補(bǔ)償高壓流體的壓縮率，做到無(wú)脈沖恒壓遞送。這種連續(xù)流和恒定壓力對(duì)于微生物破碎是必不可少的，有利于保證樣品均質(zhì)效果的均一性和穩(wěn)定性。

產(chǎn)品詳細(xì)介紹STANSTED High Pressure HomogeniserSTANSTED超高壓納米均質(zhì)機(jī) The FRENCH? Pressure Cell 是一款極為精致的實(shí)驗(yàn)型超高壓納米均質(zhì)機(jī)。采用革命性的設(shè)計(jì)理念，帶來(lái)更出色的均質(zhì)效果，更高的工作壓力，更穩(wěn)定的工作性能。液壓增強(qiáng)器工作原理，驅(qū)動(dòng)更強(qiáng)勁更穩(wěn)定；壓力平衡負(fù)載均質(zhì)作用腔和均質(zhì)作用閥體，提供更高的壓力和最佳的均質(zhì)效果；PLC控制模塊，可選擇單次、半自動(dòng)循環(huán)和全自動(dòng)循環(huán)操作；獨(dú)有的安全監(jiān)控系統(tǒng)和安全設(shè)計(jì)，使用更安全。STANSTED成立于1970年，具有豐富的超高壓設(shè)備制造經(jīng)驗(yàn)，可為用戶(hù)提供最優(yōu)的納米均質(zhì)解決方案。 1.最高工作壓力達(dá)4200bar,60000psi2.可選擇單次操作、半自動(dòng)循環(huán)和全自動(dòng)循環(huán)操作3.最小樣品量5ml4.壓力腔體及均質(zhì)閥可滅菌5.帶溫度控制6.良好的均質(zhì)重現(xiàn)性和穩(wěn)定性7.歐盟CE認(rèn)證及其它國(guó)際通用安全標(biāo)準(zhǔn)8.產(chǎn)品可線(xiàn)性放大，可提供一系列從實(shí)驗(yàn)型、中試型到生產(chǎn)型的超高壓納米均質(zhì)機(jī)。  型號(hào)1   10ml  60000psi 流量約為80ml/min型號(hào)2   18ml  30000psi 流量約為160ml/min 型號(hào)3   35ml  30000psi 流量約為300ml/min 應(yīng)用生物細(xì)胞破壁：（大腸桿菌、酵母菌、霉菌......等等）酶的分離和隔離，細(xì)菌和植物組織斷裂，細(xì)胞內(nèi)蛋白質(zhì)和核酸的回收，制備EIA測(cè)試包的病毒性抗原，phizobia和假單體的膜制備，胚芽和毒素的回收，蛋白質(zhì)純化，細(xì)胞提取制備等藥劑：微乳、脂質(zhì)體、分散劑、納米粒、納米混懸液精細(xì)化工：納米材料、納米晶體、納米乳液、香精香料等 可選配件包Type 10to20 pressure cell conversion kit  CC10/20Type 20to10 pressure cell conversion kit  CC20/10Type 10 pressure cell seal kit 5pk  PCSK-010Type 20 pressure cell seal kit 5pk PCSK-020High shear valve ref.kit   HPVS-1-VRK 尺寸：550mm*550mm*700mm重量：100kg(220lb)電源：230v 1ph 50hz STANSTED擁有實(shí)驗(yàn)型、中試型、生產(chǎn)型超高壓納米均質(zhì)機(jī)供選擇，流量從5升每小時(shí)到1200升每小時(shí)，最高工作壓力可達(dá)4200Bar(420MPa)的超高壓納米均質(zhì)機(jī)。