钁′含濞变箰鍦�-瀵岀泩濞变箰鍦哄紑鎴�

鏈櫦(f膩)鏄庡叕闁嬩簡涓€绋笉鍚矘绲�(ji茅)鍔戠殑鐢熺墿鏈夋(j墨)鐒℃(j墨)"鍏ㄥ厓"寰�(f霉)鍚堝井鐢熺墿鑲ユ枡鍙婂叾鍒跺倷鏂规硶鍜屾噳(y墨ng)鐢�,灞簬杈�(n贸ng)妤�(y猫)楂樻柊鎶€琛�(sh霉).鎵€鐢ㄨ偉鏂欏師鏂欑偤绮夌补閬庣鐨勭敓鐗╂湁姗�(j墨)鑲ュ拰绮夌补鍚庣殑鐒℃(j墨)鍖栬偉;鐢熺墿鏈夋(j墨)鑲ユ墍鐢ㄨ弻鏍偤瑙ｆ穩绮夎娊瀛㈡】鑿孊acillus amyloliquefaciens SQR鈥�9;鎵€鐢ㄥ寲鑲ョ偤纭吀閵�,閬庣７閰搁垼鍜屾隘鍖栭墍.宸ヨ棟娴佺▼鐐哄皣鍘熸枡鏍规摎(j霉)椁�(y菐ng)鍒嗛渶姹傞厤姣旀贩鍕�,鍔犲叆鍦撶洡閫犵矑姗�(j墨),闁撴瓏鎬у櫞闇ч€犵矑,鍒嗙,鏈€绲傚湪婧害鈮�50鈩冩浠朵笅鐑樺共鑷冲惈姘磋唱(zh矛)閲忔瘮浣庝簬20%,鍖呰鍗崇偤鍟嗗搧鐢熺墿鏈夋(j墨)鐒℃(j墨)"鍏ㄥ厓"寰�(f霉)鍚堝井鐢熺墿鑲ユ枡.姝ゅ伐钘濆ぇ澶ч檷浣庝簡鐢熺墿鏈夋(j墨)鐒℃(j墨)鑲ョ殑鐢熺敘(ch菐n)鎴愭湰,鎿嶄綔绨�(ji菐n)鍠�,鑲ユ枡鎴愮矑鐜囧ソ,閫犵矑鏁堢巼楂� 銆�

鐮旂櫦(f膩)闅庢/n涓€绋埄鐢ㄧ敳娈煎虎妫勭墿鍒跺倷鐢叉绱狅棘锛嶄钩閰搁垼鍜屽京(f霉)鍚堟皑鍩洪吀鎴栬偨鐨勬柟娉曘€€銆€鏈櫦(f膩)鏄庢秹鍙婁竴绋€氶亷寰敓鐗╃櫦(f膩)閰佃潶锜圭瓑鐢叉寤㈡鐗╁埗鍌欑敳娈肩礌銆侊棘锛嶄钩閰搁垼鍜屽京(f霉)鍚堟皑鍩洪吀鎴栬偨鐨勬柟娉曪紝鍏烽珨鐐虹敳娈煎虎妫勭墿鍦ㄩ紶鏉庣硸涔虫】鑿岋紙锛絹锝冿綌锝忥絺锝侊絻锝夛綄锝岋綍锝�?锝掞綀锝侊綅锝庯綇锝擄綍锝擄級锛ｏ缉锛ｏ迹锛栵紣锛愶紦鍜屾灟鑽夎娊瀛㈡】鑿岋紙锛絹锝冿綁锝岋綄锝曪綋?锝擄綍锝傦綌锝夛綄锝夛綋锛夛迹锛╋迹锛ｏ紥锛擄紩锛楋紮绋瓙娑蹭腑鐧�(f膩)閰靛悗鐛插緱锛紞涔抽吀閳ｏ紝鐒跺悗鍦ㄧ背鏇查湁锛堬肌锝擄綈锝咃綊锝囷綁锝岋綄锝曪綋?锝忥綊锝欙綒锝侊絽锛夛迹锛╋迹锛ｏ紨锛戯紨锛楋紬绋瓙娑蹭腑鐧�(f膩)閰靛悗鐛插緱寰�(f霉)鍚堟皑鍩洪吀鎴栬偨鍜岀敳娈肩礌銆傛湰鐧�(f膩)鏄庣殑鏂规硶鍙互瀵�(sh铆)鐝�(xi脿n)铦﹁煿绛夌敳娈�

鏈櫦(f膩)鏄庡叕闁嬬殑涓€绋噾灞哀鍖栫墿/Cu2O/鑱氬悺鍜笁灞ょ祼(ji茅)妲�(g貌u)绱嶇背绌哄績鐞冿紝瑭茬┖蹇冪悆鐨勭悆娈煎緸鍏�(n猫i)鍚戝渚濇鐐洪噾灞哀鍖栫墿澶氭櫠灞ゃ€佹哀鍖栦簽閵呭鏅跺堡鍜岃仛鍚″挴灞わ紝姣忓堡鍘氬害鍧囧湪10绱嶇背浠ヤ笅銆傛湰鐧�(f膩)鏄庡埄鐢ㄦā鏉垮惛闄勬柟娉曪紝閫氶亷鍒嗘鍚搁檮鐨勬柟娉曞拰鍚庣簩(x霉)鐨勬按鐔卞強閫€鐏檿鐞嗗埗鍌欏緱鍒伴噾灞哀鍖栫墿/Cu2O/鑱氬悺鍜笁灞ょ祼(ji茅)妲�(g貌u)绱嶇背绌哄績鐞冦€傛湰鐧�(f膩)鏄庡埗鍌欑殑閲戝爆姘у寲鐗�/Cu2O/鑱氬悺鍜笁灞ょ祼(ji茅)妲�(g貌u)绱嶇背绌哄績鐞冩牳娈肩祼(ji茅)妲�(g貌u)瑕�(gu墨)鏁达紝鐞冩鍘氬害鍙帶锛岄噾灞哀鍖栫墿鍜屾哀鍖栦簽閵呮櫠绮掑昂瀵稿湪10nm浠ヤ笅锛岀祼(ji茅)鏅惰唱(zh矛)閲忛珮锛屾瘮琛ㄩ潰绌嶅ぇ浜�200?m2/g銆傛湰鐧�(f膩)鏄庣殑鏂规硶绨�(ji菐n)鍠€佹垚鏈純浣庯紝鍏嬫湇浜嗗偝绲�(t菕ng)鏂规硶涓敱姘у寲閵呭埗鍌欐哀鍖栦簽閵呭洶闆ｇ殑缂洪粸(di菐n)銆�

鐧�(f膩)鑲查亷绋嬩腑绱�(x矛)鑳炵敓闀�(zh菐ng)鍜屽娈栦緷璩翠簬铔嬬櫧璩�(zh矛)鐨勫ぇ閲忓悎鎴愶紝鍦ㄩ€欎竴楂樺挤(qi谩ng)搴︾殑鍔犲伐閬庣▼涓洠鍏嶇敘(ch菐n)鐢熶竴瀹氭暩(sh霉)閲忕殑鈥滄畼娆″搧鈥濓紝鍗崇敱浜庤泲鐧借唱(zh矛)缈昏閬庣▼涓殑闅ㄦ(j墨)瑾ゅ樊銆佹姌鐤婂け鏁楃瓑鍘熷洜閫犳垚鐨勯尟(cu貌)瑾ゆ姌鐤婅泲鐧姐€�

涔宠吅鐧屾槸濂虫€ф渶甯歌鐨勬儭鎬ц叓鐦や箣涓€锛屾摎(j霉)绲�(t菕ng)瑷�(j矛)锛屽叏鐞冩瘡骞翠钩鑵虹檶 鐨勭櫦(f膩)鐥呬汉鏁�(sh霉)绱勬湁 120 钀汉锛岀磩 50 钀汉姝讳簬涔宠吅鐧屻€備钩鑵虹檶灞叏韬€� 鐤剧梾锛岀稖鍚堟不鐧傞潪甯搁棞(gu膩n)閸碉紝鍏朵腑鍖栫檪鏄笉鍙浛浠ｇ殑閲嶈鎵嬫涔嬩竴銆傜劧 鑰屽钘ヨ€愯棩甯稿皫(d菐o)鑷存不鐧傚け鏁楀強鍚庢湡鑵槫鐨勫京(f霉)鐧�(f膩)鍜岃綁(zhu菐n)绉伙紝鍤�(y谩n)閲嶅▉鑴呮偅鑰� 鐢熷瓨銆傝叓鐦ょ窗(x矛)鑳炲湪鍖栫檪涓敘(ch菐n)鐢熺殑鑰愯棩鎬у父琛ㄧ従(xi脿n)鐐哄钘ヨ€愯棩锛屽嵆鍚屾檪(sh铆)灏�(du矛) 澶氱ó绲�(ji茅)妲�(g貌u)鍜屼綔鐢ㄦ(j墨)鍒朵笉鍚岀殑鍖栫檪钘ョ墿鐢�(ch菐n)鐢熶氦鍙夎€愯棩鐨勭従(xi脿n)璞★紝瀹冩槸鍖栫檪 澶辨晽鐨勪富瑕佸師鍥犮€傝繎骞翠締锛岃叓鐦よ€愯棩绱�(x矛)鑳炴牚宸叉垚

鏈櫦(f膩)鏄庡叕闁嬩簡涓€绋湪寰祦鎺ц姱鐗囦腑鍚屾檪(sh铆)鍒╃敤鎶楀師鎶楅珨鐗圭暟鎬ц瓨(sh铆)鍒ュ拰绱�(x矛)鑳炲昂瀵稿樊鍒ュ垎閬歌叓鐦ょ窗(x矛)鑳炵殑 鏂规硶銆傛湰鐧�(f膩)鏄庢柟娉曞寘鎷涓嬫椹�:鍏堝湪浜屾哀鍖栫寰悆琛ㄩ潰鍖呰９涓€灞ゆ槑鑶狅紝鍐嶄慨椋句笂 anti-EpCAM锛岀劧鍚� 鑸囧惈鏈夎叓鐦ょ窗(x矛)鑳炵殑妯ｅ搧娣峰悎瀛佃偛锛屽鑲插悗鐨勬贩鍚堟ǎ鍝侀€氶亷鍙€�(j矛n)琛屽昂瀵稿垎閬哥殑寰祦鎺ц姱鐗囧垎閬告敹闆嗗悗锛岀敤 鏄庤啝閰堕檷瑙ｄ簩姘у寲纭呯悆琛ㄩ潰鐨勬槑鑶犲嵆鍙噵鏀炬敹闆嗙殑鑵槫绱�(x矛)鑳炪€傛湰鐧�(f膩)鏄庨€氶亷鎶楀師鎶楅珨鐗圭暟鎬ц瓨(sh铆)鍒ラ伕鎿囨€х殑 鎿�(ku貌)澶т簡鍚搁檮鑵槫绱�(x矛)鑳炵殑寰悆鑸囧叾浠栫窗(x矛)鑳炵殑灏哄宸垾锛屽垎閬告晥鐜囧強绱斿害鏇撮珮锛屽苟涓斿垎閬稿嚭渚嗙殑鑵槫绱�(x矛)鑳炶兘 澶犺閲嬫斁鍙婂煿椁�(y菐ng)锛屾椿鎬т笉鍙楀奖闊裤€�

鍦ㄥ湡澹や腑锛屽井鐢熺墿鍙互鍦ㄤ綆浜�-10MPa鐨勬按鍒嗘浠朵笅缍寔涓€瀹氱殑娲绘€э紝鎸佺簩(x霉)鍒嗚В鍦熷￥鏈夋(j墨)纰筹紝灏�(d菐o)鑷村湡澹ゅ井鐢熺墿姘村垎闄愬埗闁惧€硷紙threshold锛夊拰鍦熷￥姘村垎鐗瑰緛鏇茬窔鐨勬脯(c猫)閲忚寖鍦嶄笉鍖归厤銆傛脯(c猫)閲忚寖鍦嶄箣澶栫殑鍦熷￥姘村嫝(sh矛)鍙兘閫氶亷鍦熷￥姘村垎鐗瑰緛鏇茬窔澶栨帹寰楀埌锛屼絾閫欑ó澶栨帹閬曞弽绲�(t菕ng)瑷�(j矛)瀛�(xu茅)鍘熺悊锛屽彲鑳藉皫(d菐o)鑷寸嵅寰楃殑姘村嫝(sh矛)鍊间及绠楀嚭鐝�(xi脿n)鍤�(y谩n)閲嶅亸宸€�

閵呮哀鍖栫墿瓒呭皫(d菐o)楂旇嚜寰�1986骞磋鐧�(f膩)鐝�(xi脿n)浠ヤ締锛屽叾瓒呭皫(d菐o)姗�(j墨)鐞嗕竴鐩磋鏈牁(l菒ng)鍩熺瀛�(xu茅)瀹堕珮搴﹂棞(gu膩n)娉ㄣ€傚叿鏈夊韩渚栨帓鏂ョ殑鍏╁€�(g猫)闆诲瓙锛岀偤浠€涔堝湪楂橀仈(d谩)160澶氶枊鐖炬枃锛堢磩绛変簬闆朵笅113搴︼級涓嬩粛鐒惰兘澶犵浉浜掑惛寮曞舰鎴愰浕瀛愰厤灏�(du矛)锛屽苟鍑濊仛鎴愮偤瀹忚鐨勯噺瀛愮浉骞叉厠(t脿i)锛岄€欐槸姗簷?c猫)璋€類ц箿B(t脿i)鐗╃悊闋�(l菒ng)鍩熺殑涓€鍊�(g猫)閲嶅ぇ绉戝(xu茅)鍟忛銆�2008骞磋嚦浠婏紝閻靛熀瓒呭皫(d菐o)楂斿鏃忕殑鐧�(f膩)鐝�(xi脿n)鍜屽／澶т篃鐐鸿秴灏�(d菐o)姗�(j墨)鐞嗙殑鐮旂┒娉ㄥ叆浜嗘柊鐨勬椿鍔涖€傞毃钁楃爺绌剁殑娣卞叆锛屽緸鍍呮湁鐨勫叐澶ч潪甯歌(gu墨)瓒呭皫(d菐o)瀹舵棌鍑虹櫦(f膩)锛屽(sh铆)闅涗笂浜哄€戝緢闆ｇ洿鎺ュ緱鍒版櫘閬嶇殑瑕�(gu墨)寰嬪拰鍏辫瓨(sh铆)銆傚鏋滃嚭鐝�(xi脿n)涓€鍊�(g猫)闄ら妳鍩猴紝閻靛熀涔嬪鐨勭涓夊鏃忕殑瓒呭皫(d菐o)楂旓紝閫欎竴鎯呮硜鍙兘寰楀埌寰堝ぇ鐨勬敼鍠勩€�2019骞达紝缇庡湅(gu贸)鏂潶绂忓ぇ瀛�(xu茅)灏忕祫鍦ㄤ粙浜庨惖銆侀妳涔嬮枔鐨勯幊鍏冪礌鎵€褰㈡垚鐨勬哀鍖栫墿Nd1-xSrxNiO2钖勮啘涓櫦(f膩)鐝�(xi脿n)浜�9-15 K宸﹀彸鐨勮秴灏�(d菐o)闆绘€э紝瀹冧技涔庡叿鏈夎垏閵呮哀鍖栫墿瓒呭皫(d菐o)楂旈浼肩殑3d9鏈€澶栧堡闆诲瓙杌岄亾锛岄€欑偤闈炲父瑕�(gu墨)瓒呭皫(d菐o)姗�(j墨)鐞嗙殑鐮旂┒鎻愪緵浜嗕竴鍊�(g猫)宥勬柊鐨勫钩鑷�(t谩i)銆傜瀛�(xu茅)鐣岄潪甯搁棞(gu膩n)蹇冨畠鐨勮秴灏�(d菐o)褰㈡垚鑸囬妳姘у寲鐗╄秴灏�(d菐o)楂旀湁浣曠暟鍚岋紝鍥犳鍦ㄥ(xu茅)鐣岃繀閫熸巰璧蜂簡灏�(du矛)閹冲熀瓒呭皫(d菐o)楂旂爺绌剁殑鐔辨疆銆� 瓒呭皫(d菐o)楂斿収(n猫i)閮ㄧ殑鍠矑瀛愭縺鐧�(f膩)闇€瑕佷竴瀹氱殑鑳介噺鍗崇偤瓒呭皫(d菐o)鑳介殭锛岄€欎篃鏄秴灏�(d菐o)鎱�(t脿i)鐐轰粈涔堣兘澶犲湪涓€瀹氭韩搴︿笅绌�(w臎n)瀹氬瓨鍦ㄧ殑鍘熷洜銆傝€屽叐鍊�(g猫)闆诲瓙褰㈡垚閰嶅皪(du矛)鐨勫収(n猫i)鍦ㄥ洜绱犵洿鎺ユ焙瀹氳憲瓒呭皫(d菐o)鑳介殭鍑芥暩(sh霉)鐨勮〃鐝�(xi脿n)褰㈠紡銆傚洜姝ゆ帰娓�(c猫)闈炲父瑕�(gu墨)瓒呭皫(d菐o)楂旂殑姗�(j墨)鐞嗗晱椤岀殑棣栬浠诲嫏(w霉)鏄煡閬撹秴灏�(d菐o)鑳介殭鐨勫嚱鏁�(sh霉)褰㈠紡銆傚氨閹冲熀瓒呭皫(d菐o)楂斿(sh铆)椹�(y脿n)鑰岃█锛屽緱鍒癗d1-xSrxNiO2瓒呭皫(d菐o)钖勮啘妯ｅ搧浼间箮姣旇純鍥伴洠锛屽洜姝ゅ湅(gu贸)闅涗笂闂�(gu膩n)浜嶯d1-xSrxNiO2钖勮啘鐨勭浉闂�(gu膩n)瀵�(sh铆)椹�(y脿n)閭勪笉鏄緢澶氾紝瑷卞瀵�(sh铆)椹�(y脿n)骞朵笉鑳界洿鎺ュ弽鏄犺秴灏�(d菐o)鐨勮兘闅欏嚱鏁�(sh霉)銆傛渶杩戝崡浜ぇ瀛�(xu茅)鑱炴捣铏庡湗(tu谩n)闅�(du矛)鍜岃伓瓒婂嘲銆佹綐鏇夋櫞鍦�(tu谩n)闅�(du矛)閫氬姏鍚堜綔锛屾垚鍔熷湪Nd1-xSrxNiO2瓒呭皫(d菐o)钖勮啘妯ｅ搧涓脯(c猫)閲忓埌楂樿唱(zh矛)閲忕殑鎺冩弿闅ч亾璀滐紝璀夋槑浜哊d1-xSrxNiO2涓瓨鍦ㄥ叐椤炶秴灏�(d菐o)鑳介殭锛屼竴椤炴槸V鍨嬮毀閬撹瓬鍗冲吀鍨嬬殑d娉㈣秴灏�(d菐o)鑳介殭锛岃兘闅欐渶澶у€肩偤3.9meV锛岄€欎竴榛�(di菐n)鑸囬妳姘у寲鐗╄秴灏�(d菐o)楂斿強鍏堕浼硷紱鑰屽彟涓€椤炴槸瀹屽叏鑳介殭褰㈠紡锛坒ull gap锛夌殑闅ч亾璀滐紝鑳介殭鍊肩偤2.35meV锛岄€欎竴榛�(di菐n)鍙堣垏閵呮哀鍖栫墿涓嶄竴鑷达紝鑰岃垏閻靛熀瓒呭皫(d菐o)楂旂浉浼笺€傝伓瓒婂嘲瀵�(sh铆)椹�(y脿n)绲勫埄鐢ㄥ垎瀛愭潫澶栧欢锛圡BE锛夋妧琛�(sh霉)鍒跺倷鍑洪珮璩�(zh矛)閲忕殑Nd1-xSrxNiO3 (113)钖勮啘鍙婂叿鏈夊垵姝ヨ秴灏�(d菐o)杞�(zhu菐n)璁婄殑Nd1-xSrxNiO2 (112)钖勮啘锛岃仦娴疯檸灏忕祫閫�(j矛n)琛屼簡鍚庣簩(x霉)鐨勬矮鍖栬檿鐞嗭紝閫�(j矛n)涓€姝ュ劒(y艒u)鍖栦簡Nd1-xSrxNiO2 (112)閹冲熀钖勮啘鐨勮秴灏�(d菐o)杞�(zhu菐n)璁婃韩搴﹀強琛ㄩ潰骞虫暣搴︼紝閫欐槸瀵�(sh铆)椹�(y脿n)?z膩i)杌岄ⅱ@寰楁垚鍔熺殑闂�(gu膩n)閸靛洜绱犱箣涓€銆傞€欎竴绲�(ji茅)鏋滄彮绀轰簡Nd1-xSrxNiO2瓒呭皫(d菐o)楂旂殑鑳介殭鍑芥暩(sh霉)锛岀櫦(f膩)鐝�(xi脿n)鑸囬妳姘у寲鐗╀箣闁撴棦鏈夌浉浼间箣榛�(di菐n)涔熸湁涓嶅悓涔嬭檿锛屽苟鐐烘帴涓嬩締绻肩簩(x霉)灏�(du矛)閹冲熀瓒呭皫(d菐o)楂旈枊灞曟繁鍏ョ爺绌跺瀹氫簡鍫�(ji膩n)瀵�(sh铆)鐨勫(sh铆)椹�(y脿n)鍩虹(ch菙)銆�